Christopher Puleo, PhD
Associate Professor
Rensselaer Polytechnic Institute
troy, New York, United States
Luis Lujan, PhD
Associate Dean of Student Affairs; Associate Professor
Mayo Clinic
Rochester, Minnesota, United States
Imanuel Lerman, MD MS
Professor/CEO
UCSD/InflammaSense
La Jolla , California, United States
Alik Widge, MD, PhD
Associate Professor
University of Minnesota
Minneapolis, Minnesota, United States
Anuj Bhardwaj, SM, MBA
CEO
SecondWave Systems, Inc.
St. Paul, Minnesota, United States
This review explores the evolution of bioelectronic medicine, emphasizing the potential of closed-loop neuromodulation for brain, spinal cord, and autonomic regulation. Innovations like focused ultrasound and autonomic neurography offer new therapeutic possibilities for conditions like sepsis and chronic inflammation. Overcoming signal noise, drift, and external influences will drive precision medicine forward.